Archives of physical medicine and rehabilitation · 2026
The Impact of Hormonal Stages of Life in Women With Multiple Sclerosis: A Survey Study of the Menstrual Cycle.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Johnson Kristin A, DuBose Lyndsey E, Shah Anna A, Fling Brett W
Аннотация
OBJECTIVE: To characterize the impact of the menstrual cycle on disease symptoms, physical functions, and instrumental activities of daily living (IADLs) in American women with multiple sclerosis (MS).
DESIGN: Cross-sectional study.
SETTING: Community.
PARTICIPANTS: A sample of 343 naturally menstruating American women with MS recruited from regional and national MS databases.
INTERVENTIONS: None.
MAIN OUTCOME MEASURES: Frequency and timing of menstrual cycle effects on MS symptoms, physical functions, and IADLs.
RESULTS: Over 85% of survey participants reported an exacerbation of MS disease symptoms or difficulty with physical functions or IADLs during at least one phase of the menstrual cycle. Fatigue, pain, cognitive difficulty, and muscle weakness were the most common MS symptoms to worsen across the menstrual cycle. Most participants reported greater difficulty performing IADLs like household duties and socializing during at least one menstrual cycle phase. Moreover, 39% of participants reported greater difficulty walking, and 70% of participants indicated limited ability to exercise during at least one menstrual cycle phase. Most symptoms or functions were worse in the premenstrual and menstrual phases. Among those who experienced adverse effects of the menstrual cycle, 71% had not discussed these effects with their health care providers (rehabilitation specialists and neurologists).
CONCLUSIONS: This cross-sectional snapshot suggests that most American women with MS experience worsening of disease symptoms, physical functions, and IADLs across the menstrual cycle. Rehabilitation specialists may better address the needs of women with MS by engaging in conversations and offering strategies to address the impact of the menstrual cycle. This study addresses the expressed needs of patients by characterizing the impact of the menstrual cycle in women living with MS. This study also incorporates a holistic approach by addressing the impact of the menstrual cycle not only on MS disease symptoms but also on physical functions and IADLs.
DESIGN: Cross-sectional study.
SETTING: Community.
PARTICIPANTS: A sample of 343 naturally menstruating American women with MS recruited from regional and national MS databases.
INTERVENTIONS: None.
MAIN OUTCOME MEASURES: Frequency and timing of menstrual cycle effects on MS symptoms, physical functions, and IADLs.
RESULTS: Over 85% of survey participants reported an exacerbation of MS disease symptoms or difficulty with physical functions or IADLs during at least one phase of the menstrual cycle. Fatigue, pain, cognitive difficulty, and muscle weakness were the most common MS symptoms to worsen across the menstrual cycle. Most participants reported greater difficulty performing IADLs like household duties and socializing during at least one menstrual cycle phase. Moreover, 39% of participants reported greater difficulty walking, and 70% of participants indicated limited ability to exercise during at least one menstrual cycle phase. Most symptoms or functions were worse in the premenstrual and menstrual phases. Among those who experienced adverse effects of the menstrual cycle, 71% had not discussed these effects with their health care providers (rehabilitation specialists and neurologists).
CONCLUSIONS: This cross-sectional snapshot suggests that most American women with MS experience worsening of disease symptoms, physical functions, and IADLs across the menstrual cycle. Rehabilitation specialists may better address the needs of women with MS by engaging in conversations and offering strategies to address the impact of the menstrual cycle. This study addresses the expressed needs of patients by characterizing the impact of the menstrual cycle in women living with MS. This study also incorporates a holistic approach by addressing the impact of the menstrual cycle not only on MS disease symptoms but also on physical functions and IADLs.