Metabolic complications of acute arterial occlusions.

Metabolic complications secondary to acute arterial occlusions occurred in 7.5% of our cases. It is pointed out that the characteristic biochemical changes: 1) may already be detectable during the ischemic phase, and 2) are more pronounced after revascularization of the extremity. Their identification at the early stage is essential for preventing the serious outcome of the late stage. Amputation rates are quite high (40-50%) and mortality rates are similarly great (30-80%). The ischemic rhabdomyolysis which leads to the clinical and manifestations and biochemical alterations is the initiating pathogenic factor of this syndrome. Prophylaxis and management of these complications were reviewed.