Effect of body position during weaning from total liquid ventilation in piglets.

OBJECTIVE

To determine if change in body position improves oxygen requirements and respiratory mechanics during the transition from total liquid ventilation (TLV) to gas ventilation.

METHODS

Fourteen piglets underwent TLV, followed by a 2-hour weaning period under conventional gas ventilation. Subjects were randomized to the experimental group (Rotating - R), that was in prone position between the 10th and 30th minute of weaning, or to the static control group (Supine - S).

RESULTS

Oxygenation index was lower in the R group at 30 minutes in prone position than that in the S group (1.9 [1.6; 2.8] vs 3.5 [3.1; 5.1], p = 0.001). This difference disappeared when subjects resumed the supine position (4.2 [3.8; 4.7] and 4.7 [3.8; 5.4], p = 0.4, for the R and S groups, respectively). The change in body position did not affect respiratory system compliance or inspiratory capacity.

CONCLUSION

Prone position improved oxygenation during weaning from TLV. The effect disappeared once piglets returned to the supine position.