Archives of ophthalmology (Chicago, Ill. : 1960) · 1994
Pattern reversal visual evoked potentials following early treatment of unilateral, congenital cataract.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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McCulloch D L, Skarf B
Аннотация
OBJECTIVE: To describe the pattern reversal visual evoked potentials (VEPs) that were used to monitor and quantify early visual development following treatment for dense, unilateral, congenital cataract.
DESIGN: Longitudinal prospective study.
PATIENTS: Six infants who underwent surgery and contact lens correction before age 5 months and who had good compliance with occlusion therapy throughout the first 3 years of life.
RESULTS: Initially, VEPs from aphakic eyes showed marked abnormalities, including small amplitudes, prolonged latencies, missing components, and absent VEPs to small check sizes. Threshold check size was elevated by 3 octaves or more. With part-time occlusion of the opposite eye, VEPs normalized rapidly in the first year, but residual deficits remained to age 4 years when visual acuities were between 20/50 and 20/120 in aphakic eyes. Threshold check size clearly differentiated between aphakic and normal eyes and was the only VEP parameter that was correlated with single-letter visual acuity. Thus, threshold check size had greater clinical use than measures of pattern VEPs based on latency, amplitude, or waveform.
CONCLUSIONS: Patients treated for unilateral congenital cataract, who have early surgery and contact lens correction and comply with occlusion therapy, show a period of rapid VEP maturation and have a good visual prognosis.
DESIGN: Longitudinal prospective study.
PATIENTS: Six infants who underwent surgery and contact lens correction before age 5 months and who had good compliance with occlusion therapy throughout the first 3 years of life.
RESULTS: Initially, VEPs from aphakic eyes showed marked abnormalities, including small amplitudes, prolonged latencies, missing components, and absent VEPs to small check sizes. Threshold check size was elevated by 3 octaves or more. With part-time occlusion of the opposite eye, VEPs normalized rapidly in the first year, but residual deficits remained to age 4 years when visual acuities were between 20/50 and 20/120 in aphakic eyes. Threshold check size clearly differentiated between aphakic and normal eyes and was the only VEP parameter that was correlated with single-letter visual acuity. Thus, threshold check size had greater clinical use than measures of pattern VEPs based on latency, amplitude, or waveform.
CONCLUSIONS: Patients treated for unilateral congenital cataract, who have early surgery and contact lens correction and comply with occlusion therapy, show a period of rapid VEP maturation and have a good visual prognosis.