NPJ primary care respiratory medicine · 2025
Assessing diagnostic accuracy for asthma with home spirometry in primary care.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Myers Lynnea, Bellander Martin, Ljungberg Henrik, Isachsen Martine, Eduards Marianne, Lindman Marie, Carleborg Anna, Rosengren Maria, Jansson Magnus, Sandelowsky Hanna, Larsson Kjell, Nordlund Björn
Аннотация
The aim was to evaluate the diagnostic accuracy of lung function measurements for asthma in primary care, including trial treatment. Undiagnosed patients seeking care for asthma-like symptoms were assessed at primary healthcare centers in Sweden. Participants underwent remote or in-clinic spirometry with bronchodilator responsiveness testing (BDR), remote diurnal variability testing of forced expiratory volume in 1 s (FEV1) and peak expiratory flow (PEF) over 2-4 weeks using a home spirometry system; and if necessary, three-months trial treatment with inhaled corticosteroids. Overall, 71/123 (58%) were diagnosed with asthma. When comparing patients by asthma diagnosis, sensitivity and specificity for documented diagnosis were 9% (95% CI 3-17) and 100% (93-100) for BDR; 61% (48-72) and 58% (43-71) for FEV₁; and 76% (64-85) and 69% (55-81) for PEF. Diurnal variability testing via home spirometry showed the strongest balance among sensitivity and specificity for asthma.