Two New Zn(II)/Cd(II) Complexes: Luminescent Properties and Treatment Activity on Cardiovascular Disease.

Two new supramolecular frameworks, namely [Zn(HBTC)(H2O)2]n·n(MA) (1) and {[Cd(OBDC)2(MA)(H2O)Cl](HMA)3(H2O)10(DMA)}n (2) (H3BTC = 1,3,5-benzenetricarboxylic acid, H2OBDC = phthalic acid, MA = melamine, DMA = N,N'-dimethylacetamide), have been solvothermally prepared. In addition, the solid-state luminescent properties of 1-2 at room temperature was discussed in this article as well. Their application values on the cardiovascular disease treatment were explored and we also discussed the corresponding mechanism simultaneously. Firstly, the IL-6 and IL-18 released into the plasma was measured with indicated ELISA assay. Besides, the real time RT-PCR was also performed, while activation levels of AMPK signaling pathway was determined after compound treatment.