Does early orchidopexy improve fertility?

Cryptorchidism or undescended testis (UDT) is a common problem in the pediatric male population. While spontaneous testicular descent occurs in the majority of cases, orchidopexy is the definitive treatment in those with remaining cryptorchid testis. A long established sequela to cryptorchidism is reduced fertility in the adult male and recent guidelines have advocated for earlier orchidopexy as studies have shown improvement in fertility rates when surgery is performed before one year of age. Further studies continue to validate these recommendations as recent research demonstrates crucial developmental steps even in very young boys. These steps are critical to complete testicular maturation and a loss of these milestones has increasingly been shown to decrease fertility later in life. This review examines the histological findings, hormonal data, and paternity rates from those who have undergone orchidopexy at varying ages and summarizes current recommendations aimed at preserving fertility as much as possible in this population.