Evaluating the Role of Critical Care Ultrasonography in Predicting Volume Responsiveness Among Septic Shock Patients Undergoing Fluid Resuscitation: A Clinical Study.

This study aimed to evaluate the predictive efficacy of critical care ultrasonography for volume responsiveness in septic shock patients undergoing fluid resuscitation. Ninety septic shock patients admitted between January 2021 and December 2023 were divided into responsive and nonresponsive groups based on fluid responsiveness. Ultrasonic indices, including velocity time integration (ΔVTI), corrected flow time (ΔFTc), peak velocity of the carotid artery (ΔVpeakCA), and Respiratory Variation Index (RVI), as well as oxygen metabolism parameters, were measured before and after the fluid resuscitation trial. The correlation between ultrasonic indices and stroke volume variation (SVV) was assessed, and the predictive efficacy of these indices was analyzed using receiver operating characteristic curves. Results showed that ΔVTI, ΔFTc, ΔVpeakCA, RVI, and SVV were significantly lower in the nonresponsive group compared with the responsive group (P < 0.05). Pearson correlation analysis indicated a strong positive correlation between ΔVTI, ΔFTc, ΔVpeakCA, RVI, and SVV (r = 0.737, 0.741, 0.743, 0.739). Receiver operating characteristic analysis revealed that the areas under the curve for ΔVTI, ΔFTc, ΔVpeakCA, RVI and the combined indices were 0.944, 0.867, 0.874, and 0.935, respectively. Postresuscitation, the responsive group demonstrated significantly higher central venous oxygen saturation levelselevated partial pressure of oxygen and markedly reduced lactate levels compared with the nonresponsive group. These findings suggest that ΔVTI, ΔFTc, ΔVpeakCA, and RVI are effective for assessing volume responsiveness in mechanically ventilated septic shock patients, with the responsive group showing improved resuscitation outcomes.