Assessing the potential impact of livestock immunisation and acaricide use on controlling the spread of East Coast fever.

Immunisation of livestock with high-quality vaccines and the use of acaricides are highly ranked tick control strategies worldwide. However, the effects of coupling livestock immunisation and acaricide control on mitigating the spread of East Coast Fever (ECF) is not well understood. Effective strategies to curb the disease require an understanding of the influence of control strategies on ECF dynamics. This paper presents a new mathematical model for ECF in ticks and livestock to analyze the effect of livestock immunisation and acaricide control on preventing ECF spread. Our research is focused on examining how vaccine efficacy, inoculation rate, and acaricide efficacy affect disease progression. Our finding is that acaricide control alone may not be sufficient to stop the spread of ECF, even if it has an 80% effectiveness all the time. However, by pairing acaricide control with livestock vaccination, disease transmission is significantly reduced and elimination is possible under certain circumstances. Overall, results show that it is crucial to understand the influence of combining control strategies to mitigate the spread of this devastating livestock disease and enhance decision making among policymakers and livestock keepers.