British journal of cancer · 2011
Prostate involvement during sexually transmitted infections as measured by prostate-specific antigen concentration.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Sutcliffe S, Nevin R L, Pakpahan R, Elliott D J, Cole S R, De Marzo A M, Gaydos C A, Isaacs W B, Nelson W G, Sokoll L J, Zenilman J M, Cersovsky S B, Platz E A
Аннотация
BACKGROUND: We investigated prostate involvement during sexually transmitted infections by measuring serum prostate-specific antigen (PSA) as a marker of prostate infection, inflammation, and/or cell damage in young, male US military members.
METHODS: We measured PSA before and during infection for 299 chlamydia, 112 gonorrhoea, and 59 non-chlamydial, non-gonococcal urethritis (NCNGU) cases, and 256 controls.
RESULTS: Chlamydia and gonorrhoea, but not NCNGU, cases were more likely to have a large rise (40%) in PSA than controls (33.6%, 19.1%, and 8.2% vs 8.8%, P<0.0001, 0.021, and 0.92, respectively).
CONCLUSION: Chlamydia and gonorrhoea may infect the prostate of some infected men.
METHODS: We measured PSA before and during infection for 299 chlamydia, 112 gonorrhoea, and 59 non-chlamydial, non-gonococcal urethritis (NCNGU) cases, and 256 controls.
RESULTS: Chlamydia and gonorrhoea, but not NCNGU, cases were more likely to have a large rise (40%) in PSA than controls (33.6%, 19.1%, and 8.2% vs 8.8%, P<0.0001, 0.021, and 0.92, respectively).
CONCLUSION: Chlamydia and gonorrhoea may infect the prostate of some infected men.