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Revista medica de Chile · 2018

[Cardiotoxicity of anticancer therapies. Towards the implementation of cardio-oncology units].

СтатьяОбзорНазвание и аннотация: Перевод в очереди
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Hameau René, Gabrielli Luigi, Garrido Marcelo, Guzmán Ana María, Retamal Ignacio, Vacarezza María José, Greig Douglas, Ocqueteau Mauricio, Sánchez César, Pizarro Marcela, Corvalán Alejandro, Lavandero Sergio, Castro Pablo F, Martínez Gonzalo

Аннотация

Recently, we have witnessed major improvements in cancer treatment. Early diagnosis and development of new therapies have reduced cancer-related mortality. However, these new therapies, along with greater patient survival, are associated with an increase in untoward effects, particularly in the cardiovascular system. Although cardiotoxicity induced by oncologic treatments affects predominantly the myocardium, it can also involve other structures of the cardiovascular system, becoming one of the main causes of morbidity and mortality in those who survive cancer. The main objective of cardio-oncology is to achieve the maximum benefits of oncologic treatments while minimizing their deleterious cardiovascular effects. It harbors the stratification of patients at risk of cardiotoxicity, the implementation of diagnostic tools (imaging techniques and biomarkers) for early diagnosis, preventive strategies and early treatment options for the complications. Herein, we discuss the basic knowledge for the implementation of cardio-oncology units and their role in the management of cancer patients, the diagnostic tools available to detect cardiotoxicity and the present therapeutic options.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты