World neurosurgery · 2025
Penetrating Brain Injury: Bridging Global Disparities in Care and Advancing Management Strategies.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Ошибки и ограничения
История · было → стало
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Alvarado-Dyer Ronald, Mansour Ali, Garcia Roxanna, Puri Sameera, Videtta Walter, Rubiano Andres, Ciarrochi Nicolás, Lo Elaine, Fakhri Farima, Torbey Michel, Goldenberg Fernando D, Lazaridis Christos
Аннотация
BACKGROUND: Despite being a global health concern with significant mortality and healthcare costs, particularly in low- and middle-income countries, evidence-based guidelines tailored to penetrating brain injury (PBI) remain scarce.
METHODS: The sixth South American Regional Neurocritical Care Society Conference in Buenos Aires, in collaboration with the Argentinian Society of Critical Care and the Latin American Brain Injury Consortium, featured a session highlighting the potential benefits of intracranial pressure monitoring and early decompressive craniectomy, both of which have demonstrated survival advantages in selected patient populations but remain underused in low- and middle-income countries. Additionally, a novel imaging-based phenotyping system, the UChicago PBI Imaging score, was introduced to refine prognostication and guide intervention strategies.
RESULTS: These approaches are crucial given PBI's rising global incidence and its mounting toll on healthcare systems. A central theme of the conference was the imperative of comparative effectiveness research to address disparities in PBI management.
CONCLUSION: By systematically evaluating diverse patient populations, comparative effectiveness research can identify the most efficacious and cost-effective interventions, ensuring they are adapted to resource-limited environments. This framework holds promise for establishing standardized guidelines and informing scalable practice models across variable resource settings. Moving forward, fostering international partnerships and data-sharing initiatives will be vital for refining existing protocols and ensuring equitable access to interventions associated with improved survival. These efforts aim to advance care in PBI worldwide.
METHODS: The sixth South American Regional Neurocritical Care Society Conference in Buenos Aires, in collaboration with the Argentinian Society of Critical Care and the Latin American Brain Injury Consortium, featured a session highlighting the potential benefits of intracranial pressure monitoring and early decompressive craniectomy, both of which have demonstrated survival advantages in selected patient populations but remain underused in low- and middle-income countries. Additionally, a novel imaging-based phenotyping system, the UChicago PBI Imaging score, was introduced to refine prognostication and guide intervention strategies.
RESULTS: These approaches are crucial given PBI's rising global incidence and its mounting toll on healthcare systems. A central theme of the conference was the imperative of comparative effectiveness research to address disparities in PBI management.
CONCLUSION: By systematically evaluating diverse patient populations, comparative effectiveness research can identify the most efficacious and cost-effective interventions, ensuring they are adapted to resource-limited environments. This framework holds promise for establishing standardized guidelines and informing scalable practice models across variable resource settings. Moving forward, fostering international partnerships and data-sharing initiatives will be vital for refining existing protocols and ensuring equitable access to interventions associated with improved survival. These efforts aim to advance care in PBI worldwide.