The Journal of small animal practice · 2009
Subcutaneous pre-anaesthetic medication with acepromazine-buprenorphine is effective as and less painful than the intramuscular route.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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Gurney M, Cripps P, Mosing M
Аннотация
OBJECTIVES: To compare reaction to injection, sedation and propofol induction dose in dogs receiving acepromazine-buprenorphine pre-anaesthetic medication by the intramuscular or subcutaneous routes.
METHODS: Fifty-two client owned dogs of American Society of Anesthesiologists grade I or II anaesthetised for diagnostic imaging. Dogs were randomly assigned to receive acepromazine 0.03 mg/kg and buprenorphine 0.02 mg/kg either intramuscular or subcutaneous. Reaction to injection was scored. Sedation was compared before and one hour after pre-anaesthetic medication. Propofol was administered in 1 mg/kg incremental injections until tracheal intubation was achieved. Total propofol dose was recorded.
RESULTS: Reaction to injection was significantly greater (P=0.009) in the intramuscular group compared to the subcutaneous group. Sedation scores were not significantly different (P=0.523) between the intramuscular and the subcutaneous group. There was no statistically significant difference in propofol dose for induction (P=0.7).
CLINICAL SIGNIFICANCE: Acepromazine-buprenorphine pre-anaesthetic medication provides a similar degree of sedation whether administered by the intramuscular or subcutaneous route. The intramuscular route is more painful compared to the subcutaneous route.
METHODS: Fifty-two client owned dogs of American Society of Anesthesiologists grade I or II anaesthetised for diagnostic imaging. Dogs were randomly assigned to receive acepromazine 0.03 mg/kg and buprenorphine 0.02 mg/kg either intramuscular or subcutaneous. Reaction to injection was scored. Sedation was compared before and one hour after pre-anaesthetic medication. Propofol was administered in 1 mg/kg incremental injections until tracheal intubation was achieved. Total propofol dose was recorded.
RESULTS: Reaction to injection was significantly greater (P=0.009) in the intramuscular group compared to the subcutaneous group. Sedation scores were not significantly different (P=0.523) between the intramuscular and the subcutaneous group. There was no statistically significant difference in propofol dose for induction (P=0.7).
CLINICAL SIGNIFICANCE: Acepromazine-buprenorphine pre-anaesthetic medication provides a similar degree of sedation whether administered by the intramuscular or subcutaneous route. The intramuscular route is more painful compared to the subcutaneous route.