Vestnik oftalmologii · 2019
[Modern approaches to predicting the development of active type 1 retinopathy of prematurity].
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Petrachkova M S, Saidasheva E I, Petrachkov D V, Buyanovskaya S V
Аннотация
PURPOSE: To develop a mathematical model for predicting the development of threshold stages (type 1) of active retinopathy of prematurity (ROP) based on neonatal risk factors in premature infants.
MATERIAL AND METHODS: The study observed 69 premature infants from a perinatal center with gestation age of 22-31 weeks and birth weight of 499-1500 grams. Patients were divided into 2 groups depending on the type of ROP: the main group - 40 infants with a threshold stage (type 1) of ROP, requiring laser treatment; the control group - 29 children with spontaneous regression of the initial (1-2) stages (type 2) of the disease. A model for predicting the development of ROP threshold stage was built using mathematical justification.
RESULTS: The study established potential predictors of type 1 ROP: staying in the intensive care unit for more than 30 days (p=0.011); duration of child's staying on mechanical ventilator more than 30 days (p=0.002); parenteral nutrition for more than 13 days (p=0.013); presence of respiratory distress syndrome of 3rd degree (p<0.001); presence of bronchopulmonary dysplasia (p=0.034). These predictors were used to design a mathematical model for predicting the development of threshold stages of ROP.
CONCLUSION: The proposed prognostic model of type 1 active ROP is characterized by high information content and can be recommended for use in clinical practice of neonatal medical institutions.
MATERIAL AND METHODS: The study observed 69 premature infants from a perinatal center with gestation age of 22-31 weeks and birth weight of 499-1500 grams. Patients were divided into 2 groups depending on the type of ROP: the main group - 40 infants with a threshold stage (type 1) of ROP, requiring laser treatment; the control group - 29 children with spontaneous regression of the initial (1-2) stages (type 2) of the disease. A model for predicting the development of ROP threshold stage was built using mathematical justification.
RESULTS: The study established potential predictors of type 1 ROP: staying in the intensive care unit for more than 30 days (p=0.011); duration of child's staying on mechanical ventilator more than 30 days (p=0.002); parenteral nutrition for more than 13 days (p=0.013); presence of respiratory distress syndrome of 3rd degree (p<0.001); presence of bronchopulmonary dysplasia (p=0.034). These predictors were used to design a mathematical model for predicting the development of threshold stages of ROP.
CONCLUSION: The proposed prognostic model of type 1 active ROP is characterized by high information content and can be recommended for use in clinical practice of neonatal medical institutions.