A Case Report of Acute Renal Failure due to Amlodipine Overdose and Alcohol Consumption.

Amlodipine intoxication is clinically common yet life-threatening, usually resulting in severe cardiovascular collapse and end-organ hypoperfusion. Here, we report a case of a 46-year-old male with amlodipine (420 mg) and ethanol intoxication who unexpectedly presented without severe hypotension or shock. Instead, his main manifestation was acute renal function loss requiring hemodialysis. The potential pathological mechanism may be acute kidney injury (AKI) caused by transient renal ischemic insult, while ethanol may exacerbate acute tubular necrosis (ATN).