Postinflammatory interstitial lung injury after Glenn and Fontan circulation: a case series.

Three infants developed ARDS-like lung injury after Glenn or Fontan procedures, each following infection or inflammation. All showed unusually high elevations of epithelial injury markers such as KL-6 and surfactant protein D (SP-D). These findings suggest a distinct post-bypass phenotype in which right-heart circulation may amplify epithelial injury beyond that seen in typical paediatric ARDS.