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DOI 10.1136/rapm-2024-105430

Медицинская библиотека · Regional anesthesia and pain medicine · 2025

Rectus sheath block added to parasternal block may improve postoperative pain control and respiratory performance after cardiac surgery: a superiority single-blinded randomized controlled clinical trial.

Strumia Alessandro, Pascarella Giuseppe, Sarubbi Domenico, Di Pumpo Annalaura, Costa Fabio, Conti Maria Cristina, Rizzo Stefano, Stifano Mariapia, Mortini Lara, Cassibba Alessandra, Schiavoni Lorenzo, Mattei Alessia, Ruggiero Alessandro, Agrò Felice E, Carassiti Massimiliano, Cataldo Rita

Equivalence TrialСтатьяРандомизированное исследованиеПеревод в очереди

Аннотация

BACKGROUND

The population undergoing cardiac surgery confronts challenges from uncontrolled post-sternotomy pain, with possible adverse effects on outcome. While the parasternal block can improve analgesia, its coverage may be insufficient to cover epigastric area. In this non-blinded randomized controlled study, we evaluated the analgesic and respiratory effect of adding a rectus sheath block to a parasternal block.

METHODS

58 patients undergoing cardiac surgery via median sternotomy were randomly assigned to receive parasternal block with rectus sheath block (experimental) or parasternal block with epigastric exit sites of chest drains receiving surgical infiltration of local anesthetic (control). The primary outcome of this study was pain at rest at extubation. We also assessed pain scores at rest and during respiratory exercises, opiate consumption and respiratory performance during the first 24 hours after extubation.

RESULTS

The median (IQR) maximum pain scores (on a 0-10 Numeric Rate Scale (NRS)) at extubation were 4 (4, 4) in the rectus sheath group and 5 (4, 5) in the control group (difference 1, p value=0.03). Rectus sheath block reduced opioid utilization by 2 mg over 24 hours (IC 95% 0.0 to 2.0; p<0.01), reduced NRS scores at other time points, and improved respiratory performance at 6, 12, and 24 hours after extubation.

CONCLUSION

The addition of a rectus sheath block with a parasternal block improves analgesia for cardiac surgery requiring chest drains emerging in the epigastric area.

TRIAL REGISTRATION NUMBER: NCT05764616.

Для цитирования: Strumia Alessandro, Pascarella Giuseppe, Sarubbi Domenico, Di Pumpo Annalaura, Costa Fabio, Conti Maria Cristina, Rizzo Stefano, Stifano Mariapia, Mortini Lara, Cassibba Alessandra, Schiavoni Lorenzo, Mattei Alessia, Ruggiero Alessandro, Agrò Felice E, Carassiti Massimiliano, Cataldo Rita. Rectus sheath block added to parasternal block may improve postoperative pain control and respiratory performance after cardiac surgery: a superiority single-blinded randomized controlled clinical trial.. Regional anesthesia and pain medicine. 2025. DOI: 10.1136/rapm-2024-105430.

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