Revista da Escola de Enfermagem da U S P · 2025
Evaluation of the effectiveness of solutions for clearing neonatal central venous catheters: randomized study.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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Mathiolli Carolina, Araujo Juliane Pagliari, Pinto Keli Regiane Tomeleri da Fonseca, Pimenta Rosangela Aparecida, Venturini Danielle, Marcon Sonia Silva, Zani Adriana Valongo
Аннотация
OBJECTIVE: To evaluate the effectiveness of saline, heparin, and vitamin C solutions in unclogging neonatal central venous catheters occluded by clots.
METHOD: A randomized, double-blind, in vitro experimental study conducted in August 2022 with 90 neonatal central venous catheters occluded with blood that remained in a water bath for 8 hours. The solutions tested were: saline, heparin (50 mg/ml), and vitamin C (25 mg/ml), using a negative pressure technique. The variables of number of attempts and time to unclogging were evaluated in relation to the mean and standard deviation. For variables with abnormal distribution, the Kruskal-Wallis test was used.
RESULTS: There was no statistical significance in relation to the time and number of attempts to unclog the three solutions (p > 0.05), and the maximum time to unclog the catheters was 120 minutes.
CONCLUSION: The three substances showed similar results. Thus, saline solution is recommended because it is considered safe, with fewer side effects when used in newborns.
METHOD: A randomized, double-blind, in vitro experimental study conducted in August 2022 with 90 neonatal central venous catheters occluded with blood that remained in a water bath for 8 hours. The solutions tested were: saline, heparin (50 mg/ml), and vitamin C (25 mg/ml), using a negative pressure technique. The variables of number of attempts and time to unclogging were evaluated in relation to the mean and standard deviation. For variables with abnormal distribution, the Kruskal-Wallis test was used.
RESULTS: There was no statistical significance in relation to the time and number of attempts to unclog the three solutions (p > 0.05), and the maximum time to unclog the catheters was 120 minutes.
CONCLUSION: The three substances showed similar results. Thus, saline solution is recommended because it is considered safe, with fewer side effects when used in newborns.