Медицинская библиотека · Transplantation proceedings · 2005

Survival beyond 10 years following heart transplantation: The Cleveland Clinic Foundation experience.

Ozduran V, Yamani M H, Chuang H-H, Sipahi I, Cook D J, Sendrey D, Tong L, Hobbs R, Rincon G, Bott-Silverman C, James K, Taylor D O, Young J B, Navia J, Banbury M, Smedira N, Starling R C

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Аннотация

BACKGROUND

Long-term survival after heart transplantation is a desirable although challenging goal.

METHODS

We analyzed clinical outcomes in the cohort of 170 patients who have undergone heart transplantation at The Cleveland Clinic Foundation and survived >10 years.

RESULTS

We found 10-year and 15-year survival rates of 54% and 41%, respectively, in these patients, but there was also a high incidence of complications, such as hypertension, renal dysfunction, transplant vasculopathy, and malignancy.

CONCLUSIONS

Long-term survival following cardiac transplantation is possible although complications are frequent. Beyond 10 years, malignancy is a major cause of death.

Для цитирования: Ozduran V, Yamani M H, Chuang H-H, Sipahi I, Cook D J, Sendrey D, Tong L, Hobbs R, Rincon G, Bott-Silverman C, James K, Taylor D O, Young J B, Navia J, Banbury M, Smedira N, Starling R C. Survival beyond 10 years following heart transplantation: The Cleveland Clinic Foundation experience.. Transplantation proceedings. 2005. DOI: 10.1016/j.transproceed.2005.10.021.

Предметные рубрики MeSH

Adult Cohort Studies Female Graft Rejection Heart Transplantation Humans Immunosuppression Therapy Male Middle Aged Retrospective Studies Survival Analysis Survivors Time Factors Tissue Donors

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