Harnessing Electrochemistry for Direct Deoxygenative Silylation of Alcohols and Ketones.

Alcohols and ketones are abundant and structurally diverse feedstocks, yet their direct transformation into organosilicon compounds remains challenging due to the difficulty in selective cleaving C─OH and C═O bonds. Here, we report an electrochemically driven deoxygenative C─Si bond formation strategy that converts alcohols and ketones directly to organosilicon compounds. The reactions operate under mild conditions without external redox reagents and sacrificial electrodes. A wide range of alcohols, including primary, secondary, and tertiary alcohols, as well as ketones, are efficiently converted to the corresponding organosilane products. Overall, this study provides a step-economical, highly efficient, and synthetically versatile platform for the direct conversion of feedstock chemicals into valuable organosilicon compounds.