Multicentric Castleman Disease: A Case Report of an Arab Female.

We report the case of a 74-year-old female, who presented with a two-month history of fever, night sweats, and lymphadenopathy. She was thoroughly investigated, with high clinical suspicion for lymphoma. However, lymph node biopsy results revealed histopathological features of a hyaline vascular variant of Castleman disease. Owing to the involvement of multiple lymph node regions and the presence of systemic symptoms, the patient was diagnosed with multicentric Castleman disease and was started on steroid therapy, as well as anti-interleukin-6 (anti-IL-6) therapy, namely, tocilizumab, for the management of this condition. The patient responded well to the treatment and was discharged home in stable condition.