[Pregnancy of patients conceived within one year after chemotherapy for gestational trophoblastic tumor].

OBJECTIVE

To explore the risk of pregnancy in patients conceived within one year after successful chemotherapy for gestational trophoblastic tumor.

METHODS

22 patients conceived within one year after chemotherapy were followed up and analysed about abnormal pregnant result, wastage rate and the time of interval between chemotherapy and pregnancy.

RESULTS

Among 22 cases, 9 cases were full term birth, 6 cases were wastage. The wastage rate was 27.3%. The wastage rate of these patients conceived within half a year was higher than one year (P < 0.05). 1 repeated hydatidiform mole and one post term choriocarcinoma occurred in 22 patients. They both were conceived within 5 months after chemotherapy.

CONCLUSIONS

Preservation of fertility is feasible in patients suffering from choriocarcimona and invasive mole. But these patients should practise contraception at least half a year after chemotherapy, and it's better to advise patients to take contraception for one year.