Fertility and sterility · 1996
Incongruent follicular development reduces gamete intrafallopian transfer pregnancy rate.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
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Rombauts L, Webster D, Wood C E, Healy D L
Аннотация
OBJECTIVE: To test the null hypothesis that asymmetric or incongruent follicular development does not influence GIFT pregnancy rates (PRs).
DESIGN: A prospective comparative study.
SETTING: Tertiary referral center for infertility.
PATIENT(S): Ninety-three consecutive infertile patients having GIFT.
INTERVENTION(S): Controlled ovarian hyperstimulation and GIFT.
MAIN OUTCOME MEASURE(S): The incongruity ratio as a parameter of the asymmetry in follicular development and the clinical PR.
RESULT(S): An inverse relationship was observed between the degree of incongruity and the clinical PRs. In patients with an incongruity ratio < 1.5, the clinical PR was 56.1%. In patients with an incongruity ratio > or = 1.5, the clinical PR was only 17.3%.
CONCLUSION(S): Incongruent follicular development during controlled ovarian hyperstimulation has a marked negative influence on the outcome of GIFT cycles. Factors such as side of the gamete transfer and oocyte quality did not account for the observed differences.
DESIGN: A prospective comparative study.
SETTING: Tertiary referral center for infertility.
PATIENT(S): Ninety-three consecutive infertile patients having GIFT.
INTERVENTION(S): Controlled ovarian hyperstimulation and GIFT.
MAIN OUTCOME MEASURE(S): The incongruity ratio as a parameter of the asymmetry in follicular development and the clinical PR.
RESULT(S): An inverse relationship was observed between the degree of incongruity and the clinical PRs. In patients with an incongruity ratio < 1.5, the clinical PR was 56.1%. In patients with an incongruity ratio > or = 1.5, the clinical PR was only 17.3%.
CONCLUSION(S): Incongruent follicular development during controlled ovarian hyperstimulation has a marked negative influence on the outcome of GIFT cycles. Factors such as side of the gamete transfer and oocyte quality did not account for the observed differences.