Effectiveness and safety of intravenous iron sucrose in correcting ferritin level for female patients with iron deficiency anemia.

OBJECTIVE

Aim: The study aims to evaluate the effectiveness and safety of intravenous iron sucrose in correcting serum ferritin in female patients with iron deficiency anemia.

PATIENTS AND

METHODS

Materials and

Methods

A prospective clinical study was conducted at Alsader Medical City in AlNajaf City/ Iraq. We enrolled 100 female patients with iron deficiency anemia, and hemoglobin less than 12 mg/dl. Two hundred mg of elemental iron was given twice weekly over 2.5 hours, and the patients were observed closely for any potential side effects. The main effectiveness endpoint gained from variation in serum ferritin and hemoglobin from baseline to end of the study. The safety evaluation includes recording any side effects developed either during or after intravenous administration.

RESULTS

Results

The mean of hemoglobin concentration at bassline was 8.05±0.891 mg/dl, and the mean of hemoglobin after one month of treatment was 11.234±1.232G/dl,(p <0.0001). There was an increase in serum ferritin concentration from the beginning of the study with 10.2±0.23ng/dl to 224.12±0.772 ng/dl, (p<0.0001) after 1 month of treatment. No one of the patients had any serious or lethal side effects.

CONCLUSION

Conclusions

Intravenous iron sucrose is an effective and safe option for the correction of serum ferritin in female patients with iron deficiency anemia.