Neurology · 2010
Anatomical correlate of positive spontaneous visual phenomena: a voxelwise lesion study.
Сравнительное исследованиеСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Baier B, de Haan B, Mueller N, Thoemke F, Birklein F, Dieterich M, Karnath H-O
Аннотация
OBJECTIVES: Visual phenomena such as phosphenes, photopsias, or complex visual hallucinations occur in patients with lesions affecting the occipital, parietal, or temporal lobe. Whether these phenomena are provoked by lesions in specific anatomical regions is still uncertain. To determine which brain regions might be involved in such visual phenomena, we used new brain imaging and lesion analysis tools that allow a direct comparison with control patients.
METHODS: Visual phenomena were investigated in a total of 23 patients with acute infarctions along the visual pathways (6 patients with left-sided and 17 patients with right-sided lesions).
RESULTS: Ten of these 23 patients (43%) reported positive spontaneous visual phenomena (PSVP). Nine of the 10 patients (90%) with PSVP reported phosphenes; only 3 of the 10 (30%) reported photopsias. Statistical voxelwise lesion-behavior mapping revealed that the areas specifically related to PSVP are V1, V2, and the optic radiation.
CONCLUSIONS: Disinhibition of earlier visual areas after lesions of the visual cortex and its afferent fibers seems to be the crucial mechanism in the genesis of visual phenomena in acute stroke patients.
METHODS: Visual phenomena were investigated in a total of 23 patients with acute infarctions along the visual pathways (6 patients with left-sided and 17 patients with right-sided lesions).
RESULTS: Ten of these 23 patients (43%) reported positive spontaneous visual phenomena (PSVP). Nine of the 10 patients (90%) with PSVP reported phosphenes; only 3 of the 10 (30%) reported photopsias. Statistical voxelwise lesion-behavior mapping revealed that the areas specifically related to PSVP are V1, V2, and the optic radiation.
CONCLUSIONS: Disinhibition of earlier visual areas after lesions of the visual cortex and its afferent fibers seems to be the crucial mechanism in the genesis of visual phenomena in acute stroke patients.