[Application of auditory brainstem response in hearing impairment and prognosis of neonatal hypoxic ischemic encephalopathy].

Objective

To investigate the effect of auditory brainstem response in hearing impairment and prognosis of neonatal hypoxic ischemic encephalopathy（HIE）. Method:Forty-five children with HIE admitted were enrolled. All patients were tested for auditory brainstem response and followed up for 3 years to observe the prognosis of the children. Result:A total of 90 ears were included in 45 children, of which 77 ears had hearing impairment, accounting for 85.6%; 38 ears had mild hearing impairment, accounting for 49.4%; 19 ears had moderate hearing impairment, accounting for 24.7%; 20 ears had severe hearing impairment, accounting for 26.0%; the difference was statistically significant（P<0.05）. Children with moderate and severe HIE had better hearing impairment than children with mild HIE. Serious, the difference was statistically significant（χ²=7.921, P=0.009）. A total of 90 ears were included in 45 patients, 40 of whom completed 3 years of follow-up. The prognosis of children with hearing threshold ≤60 dBnHL was worse than the threshold ≥61 dBnHL, and the difference was statistically significant（P=0.001）. Abnormal manifestations of auditory brainstem response were mainly in 13 children with mild HIE（76.5%） with poor differentiation or prolongation of Ⅰwave PL; 26 patients with moderate and severe HIE（92.9%） With Ⅲ, Ⅴ wave PL extension, Ⅲ-Ⅴ wave IPL extension, Ⅰ-Ⅲ wave IPL extension, Ⅰ-Ⅴ wave PL extension, Ⅰ-Ⅲ/Ⅲ-Ⅴ wave IPL wave interval ratio less than 1, and Ⅴ/Ⅰ amplitude less than 0.5.

Conclusion

The auditory brainstem response in the hearing impairment and prognosis of HIE can effectively reflect the relationship between the severity of HIE and the severity of hearing impairment, and the relationship between the prognosis of children and the severity of hearing impairment. It can be used as an effective means to help determine the degree of HIE hearing loss and prognosis.