[Agranulocytosis induced by rifamycin SV in a patient with Hodgkin's disease. Immunologic considerations and pathogenetic interpretations].

Alter a comprehensive introduction, intended to vocalize the pharmacologically-induced leukopenia problem, it is herein described an agranulocytosis case, Rifamicin SV-induced, in an abdominal Hodgkin subject. In the process determinism, much probably immunological, we deem two factors, at least, having acted in convergence: the Rifamicin haptenic activity and the immunosuppressive action of the same. We also believe that, in the pathogenesis of the hematological situation observed, a fundamental role must be ascribed to the immuno-deficient conditions peculiar to patients affected by Hodgkin's disease.