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DOI 10.1111/ctr.15114

Медицинская библиотека · Clinical transplantation · 2023

Impact of new allocation system on length of stay following heart transplantation in the United States.

Doulamis Ilias P, Gemelli Marco, Rempakos Athanasios, Tzani Aspasia, Oh Nicholas A, Kampaktsis Polydoros, Guariento Alvise, Kuno Toshiki, Alvarez Paulino, Briasoulis Alexandros

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Аннотация

BACKGROUND

United Network for Organ Sharing (UNOS) allocation criteria changed in 2018 to accommodate the increased prevalence of ventricular assist device use as a bridge to heart transplant, which consequently prioritized sicker patients. We aimed to assess the impact of this new allocation policy on the length of stay following heart transplantation. Secondary outcomes include other risk factors for prolonged hospitalization and its effect on mortality and postoperative complications.

METHODS

The UNOS Registry was queried to identify patients who underwent isolated heart transplants in the United States between 2001 and 2023. Patients were divided into quartiles according to their respective length of stay.

RESULTS

A total of 57 020 patients were included, 15 357 of which were allocated with the new system. The median hospital length of stay was 15 days (mean 22.7 days). Length of stay was longer in the new allocation era (25 ± 30 vs. 22 ± 27 days, p < .001). The longer length of stay was associated with increased 5-year mortality in the new allocation system (aHR: 1.18; 95% CI: 1.15, 1.20; p-value: < .001).

CONCLUSION

Longer hospital stays and associated observed increased risk for mortality in the era after the allocation criteria change reflect the rationale of this shift which was to prioritize heart transplants for sicker patients. Further studies are needed to track the progress of surgical and perioperative management of these studies over time.

Для цитирования: Doulamis Ilias P, Gemelli Marco, Rempakos Athanasios, Tzani Aspasia, Oh Nicholas A, Kampaktsis Polydoros, Guariento Alvise, Kuno Toshiki, Alvarez Paulino, Briasoulis Alexandros. Impact of new allocation system on length of stay following heart transplantation in the United States.. Clinical transplantation. 2023. DOI: 10.1111/ctr.15114.

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