Chest · 2022
A 21-Year-Old Man With Dyspnea, Wheezing, and Cough.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Majumdar Uddalak, Hatipoğlu Umur, Stoller James K
Аннотация
A 21-year-old male college student presented for a second opinion with low alpha-1 antitrypsin (AAT) levels and complaints of episodic dyspnea with wheezing and cough. He was a never smoker with a medical history of frequent respiratory tract infections in early childhood and allergy to dander, dust mites, peanuts, and eggs. There was no travel history outside of the continental United States. His mother had asthma. His symptoms were not controlled on inhaled corticosteroids and bronchodilators. His AAT genotype was found to be PI∗SZ, and augmentation therapy (with pooled human-plasma derived AAT) was recommended locally.
Предметные рубрики MeSH
Anti-Asthmatic AgentsAntibodies, Monoclonal, HumanizedAsthmaCoughDiagnosis, DifferentialDyspneaForced Expiratory VolumeHumansMalePulmonary Diffusing CapacityResidual VolumeRespiratory Function TestsRespiratory SoundsTomography, X-Ray ComputedTotal Lung CapacityVital CapacityYoung Adultalpha 1-Antitrypsinalpha 1-Antitrypsin Deficiency