European journal of case reports in internal medicine · 2021
Severe Complication of Thiopurine Treatment in a Young Woman with Crohn's Disease.
СтатьяНазвание и аннотация: Перевод в очереди
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Voet Mpj, Calon Tga, Hendriks Mmc, Schreuder R M
Аннотация
CASE DESCRIPTION: A 28-year old woman receiving thiopurine treatment for Crohn's disease presented with a systemic primo cytomegalovirus (CMV) infection affecting the gut (colitis), liver (hepatitis), lungs (pneumonitis) and eyes (retinitis). Secondary to this systemic infection, she developed splenomegaly, pancytopenia and lymphadenopathy. Anti-viral treatment resulted in complete resolution of clinical, biochemical and radiological abnormalities within 6 weeks.
CONCLUSION: Early recognition is crucial since CMV infection in a patient receiving thiopurine treatment may result in serious complications.
LEARNING POINTS: Cytomegalovirus (CMV) infection in patients receiving thiopurine treatment may result in serious complications.This case report describes extensive primo CMV infection causing colitis, hepatitis, pneumonitis and retinitis in a patient receiving thiopurine treatment.Early recognition and treatment of the infection is crucial.
CONCLUSION: Early recognition is crucial since CMV infection in a patient receiving thiopurine treatment may result in serious complications.
LEARNING POINTS: Cytomegalovirus (CMV) infection in patients receiving thiopurine treatment may result in serious complications.This case report describes extensive primo CMV infection causing colitis, hepatitis, pneumonitis and retinitis in a patient receiving thiopurine treatment.Early recognition and treatment of the infection is crucial.