Presse medicale (Paris, France : 1983) · 2005
[Klinefelter's syndrome diagnosed three years after surgery for mediastinal teratoma].
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Margery J, Le Berre J P, Bredin C, Bordier L, Dupuy O, Mayaudon H, Guigay J, Bauducea B
Аннотация
INTRODUCTION: The association between some types of tumor and Klinefelter's syndrome (KS) is often missed and diagnosis of the latter delayed, as in this case report.
CASE: We present the case of a 20 year-old patient for whom KS was not diagnosed until three years after thoracic surgery for a mediastinal teratoma.
DISCUSSION: The association between KS and mediastinal germ-cell tumors is not coincidental; it illustrates the relation between aneuploidy and oncogenesis. In a young adult male, palpation of the scrotum to look for microorchidism is justified when these tumors are diagnosed because 25% occur in patients with KS.
CASE: We present the case of a 20 year-old patient for whom KS was not diagnosed until three years after thoracic surgery for a mediastinal teratoma.
DISCUSSION: The association between KS and mediastinal germ-cell tumors is not coincidental; it illustrates the relation between aneuploidy and oncogenesis. In a young adult male, palpation of the scrotum to look for microorchidism is justified when these tumors are diagnosed because 25% occur in patients with KS.