Clinical variability of bacterial vaginosis and trichomoniasis.

Bacterial vaginosis and trichomoniasis are two of the most commonly encountered vaginal diseases. Although risk factors for both vaginal conditions have been identified, there continues to be lack of knowledge in regard to their role in association with other sexually transmitted diseases. Vaginal pH is an essential ingredient in the defense and control of the vaginal environment. The alteration of pH with the sequelae of such pregnancy complications as preterm delivery, preterm labor and premature rupture of the membranes; amniotic fluid infection; postpartum endometritis and surgical infections; and the role of bacterial vaginosis are discussed. Treatment modalities in both the nonpregnant and pregnant woman, as well as treatment of resistant cases of both vaginal conditions, are recommended.