Gastrointestinal endoscopy · 2026
Role of prophylactic antibiotics in patients undergoing endoscopic ultrasound-directed transgastric interventions in Roux-en-Y gastric bypass and endoscopic ultrasound gastroenterostomy.
СтатьяМногоцентровое исследованиеНазвание и аннотация: Перевод в очереди
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Boortalary Tina, Patel Akash, Tran Tammy, Mann Rupinder, Inamdar Sumant, Di Cocco Bianca, D'Souza Lionel S, Rizzatti Gianenrico, Larghi Alberto, Oza Veeral, Bilal Mohammad, Maniak Agnieszka M, Waxman Irving, Singh Ajaypal, Kamal Faisal, Schlachterman Alexander, Kowalski Thomas, Kumar Anand
Аннотация
BACKGROUND AND AIMS: The infection risk associated with EUS-directed transgastric intervention (EDGI) and EUS-guided gastroenterostomy (EUS-GE) is unknown. We aim to investigate the effect of prophylactic antibiotics in EDGI and EUS-GE on infection-related outcomes.
METHODS: A multicenter retrospective chart review was conducted among patients who had undergone EDGI or EUS-GE between June 2017 and September 2023. Statistical significance was set at P < .05.
RESULTS: A total of 263 patients (147 EUS-GE and 116 EDGI) were identified. Prophylactic antibiotics were given in 58.9% of patients. There was no significant difference in the rate of transient (17.4% vs 12.0%; P = .23) or persistent signs of infection (4.5% vs 3.7%; P = 1.00) in patients with and without prophylactic antibiotics, respectively. The length of stay and readmission rates were also not significantly different between the 2 groups.
CONCLUSIONS: Prophylactic antibiotics for EDGI and EUS-GE did not significantly improve infection-related outcomes.
METHODS: A multicenter retrospective chart review was conducted among patients who had undergone EDGI or EUS-GE between June 2017 and September 2023. Statistical significance was set at P < .05.
RESULTS: A total of 263 patients (147 EUS-GE and 116 EDGI) were identified. Prophylactic antibiotics were given in 58.9% of patients. There was no significant difference in the rate of transient (17.4% vs 12.0%; P = .23) or persistent signs of infection (4.5% vs 3.7%; P = 1.00) in patients with and without prophylactic antibiotics, respectively. The length of stay and readmission rates were also not significantly different between the 2 groups.
CONCLUSIONS: Prophylactic antibiotics for EDGI and EUS-GE did not significantly improve infection-related outcomes.