European journal of gynaecological oncology · 2013
Correlation of subclinical HPV infection with genital warts and cervical erosion.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Cao X, Gao N, Huang L, Yao J
Аннотация
OBJECTIVE: To investigate the correlation of subclinical human papillomavirus (HPV) infection (SPI) with genital warts and cervical erosion.
MATERIALS AND METHODS: The questionnaire was firstly conducted in experimental groups (genital warts + cervical erosion), and then cervical liquid-based cytology was performed, followed by colposcopy and pathological diagnosis. In the control group, cervical liquid-based cytology and pathological diagnosis were performed. Hybrid Capture 2 assay (HC2) was conducted to detect the cervical high-risk HPV DNA.
RESULTS: The positive rate of cervical SPI in experimental groups were significantly higher than control group (p < 0.01), and in the genital warts group it was significantly higher than cervical erosion group (p < 0.05). There was no significant difference of SPI positive rate for cervical erosion with different area and degree (p > 0.05). Compared to control group, the detection rates of cervical high-risk HPV DNA in the experimental groups significantly increased (p < 0.01), and the difference between vulvar condyloma and cervical erosion groups was not statistically significant (p < 0.05). The detection rate of high-risk HPV DNA in positive SPI cases was significantly higher than negative SPI cases.
CONCLUSIONS: Women with genital warts and cervical erosion are high-risk individuals for cervical cancer, and deserve a focused initial and follow-up management.
MATERIALS AND METHODS: The questionnaire was firstly conducted in experimental groups (genital warts + cervical erosion), and then cervical liquid-based cytology was performed, followed by colposcopy and pathological diagnosis. In the control group, cervical liquid-based cytology and pathological diagnosis were performed. Hybrid Capture 2 assay (HC2) was conducted to detect the cervical high-risk HPV DNA.
RESULTS: The positive rate of cervical SPI in experimental groups were significantly higher than control group (p < 0.01), and in the genital warts group it was significantly higher than cervical erosion group (p < 0.05). There was no significant difference of SPI positive rate for cervical erosion with different area and degree (p > 0.05). Compared to control group, the detection rates of cervical high-risk HPV DNA in the experimental groups significantly increased (p < 0.01), and the difference between vulvar condyloma and cervical erosion groups was not statistically significant (p < 0.05). The detection rate of high-risk HPV DNA in positive SPI cases was significantly higher than negative SPI cases.
CONCLUSIONS: Women with genital warts and cervical erosion are high-risk individuals for cervical cancer, and deserve a focused initial and follow-up management.