American journal of translational research · 2021
The postoperative analgesic effect of intercostal nerve block and intravenous patient-controlled analgesia on patients undergoing lung cancer surgery.
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Xu Jinghong, Pu Meiting, Xu Xia, Xiang Jingguo, Rong Xueqin
Аннотация
OBJECTIVE: This research investigated the combined analgesic effects of intercostal nerve block and intravenous patient-controlled analgesia (IV-PCA) on patients after lung cancer surgery.
METHODS: 95 patients with thoracoscopic radical resection of lung cancer from April 2017 to July 2020 were enrolled as the research objects, and randomly divided into observation-group (n=50) and control-group (n=45) by random number table. The control-group received intravenous patient-controlled analgesia (IV-PCA), and the observation group received combinative treatment of intercostal nerve block and IV-PCA. The changes of VAS scores and Ramsay sedation scores postoperatively, the satisfaction with analgesia of patients, the number of IV-PCA pump compressions and the incidence of postoperative anaesthetic-related adverse reactions were compared between the two groups.
RESULTS: The VAS score of the observation-group was markedly lower than that of the control-group 2 h, 4 h, 8 h, 12 h and 24 h after surgery (P<0.05). There was no statistically significant difference in Ramsay sedation scores between the two groups 2 h, 4 h, 8 h, 12 h and 24 h after surgery (P>0.05). The satisfaction score of analgesia and the times of IV-PCA pump compressions of the observation group were obviously less than those of the control group (P<0.05). The incidences of nausea and emesia, bradycardia and somnolence between the two groups of objects were statistically insignificant (P>0.05).
CONCLUSION: The combinative treatment of intercostal nerve block and IV-PCA is safe and have obviously postoperative analgesic effect on patients undergoing thoracoscopic resection of lung cancer.
METHODS: 95 patients with thoracoscopic radical resection of lung cancer from April 2017 to July 2020 were enrolled as the research objects, and randomly divided into observation-group (n=50) and control-group (n=45) by random number table. The control-group received intravenous patient-controlled analgesia (IV-PCA), and the observation group received combinative treatment of intercostal nerve block and IV-PCA. The changes of VAS scores and Ramsay sedation scores postoperatively, the satisfaction with analgesia of patients, the number of IV-PCA pump compressions and the incidence of postoperative anaesthetic-related adverse reactions were compared between the two groups.
RESULTS: The VAS score of the observation-group was markedly lower than that of the control-group 2 h, 4 h, 8 h, 12 h and 24 h after surgery (P<0.05). There was no statistically significant difference in Ramsay sedation scores between the two groups 2 h, 4 h, 8 h, 12 h and 24 h after surgery (P>0.05). The satisfaction score of analgesia and the times of IV-PCA pump compressions of the observation group were obviously less than those of the control group (P<0.05). The incidences of nausea and emesia, bradycardia and somnolence between the two groups of objects were statistically insignificant (P>0.05).
CONCLUSION: The combinative treatment of intercostal nerve block and IV-PCA is safe and have obviously postoperative analgesic effect on patients undergoing thoracoscopic resection of lung cancer.