American journal of obstetrics and gynecology · 1996
An incremental dosing protocol for women with severe vaginal trichomoniasis and adverse reaction to metronidazole.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Pearlman M D, Yashar C, Ernst S, Solomon W
Аннотация
OBJECTIVE: Our purpose was to develop and test an incremental dosing protocol for women with adverse reaction to metronidazole and severe symptomatic Trichomonas vaginitis.
STUDY DESIGN: Two women with documented Trichomonas infection and presumed metronidazole allergy were initially treated with a number of alternative methods without success. With persistent severe symptoms associated with their infection, these women were admitted to the hospital and underwent an intravenous incremental metronidazole dosing protocol.
RESULTS: Both patients were successfully treated without adverse event. They are both symptom-free and apparently cured several months after treatment.
CONCLUSION: This protocol offers a new therapeutic option to women with adverse metronidazole reactions and severe symptomatic Trichomonas vaginitis resistant to treatment with nonmetronidazole therapy.
STUDY DESIGN: Two women with documented Trichomonas infection and presumed metronidazole allergy were initially treated with a number of alternative methods without success. With persistent severe symptoms associated with their infection, these women were admitted to the hospital and underwent an intravenous incremental metronidazole dosing protocol.
RESULTS: Both patients were successfully treated without adverse event. They are both symptom-free and apparently cured several months after treatment.
CONCLUSION: This protocol offers a new therapeutic option to women with adverse metronidazole reactions and severe symptomatic Trichomonas vaginitis resistant to treatment with nonmetronidazole therapy.