Autonomic dysfunction in left ventricular hypertrabeculation/noncompaction.

The findings of Kawasaki et al. [T. Kawasaki, A. Azuma, T. Taniguchi, et al. Heart rate variability in adult patients with isolated left ventricular noncompaction. Int J Cardiol 2005;99:147-150.] raise the following questions: why was dilated cardiomyopathy not investigated? How many of the patients with left ventricular hypertrabeculation/noncompaction (LVHT) showed abnormalities in the resting ECG and in the 24-h-Holter-monitoring? Was there any correlation with extension of LVHT and heart rate variability? Were the patients investigated neurologically and did they show other signs of autonomic dysfunction? To assess vegetative activity in LVHT patients, more comprehensive testing than simply Holter-monitoring is required.