1,3'-Dimethyl-2-oxo-6'-phenyl-7'H-spiro-[indoline-3,4'-isoxazolo[5,4-b]pyridine]-5'-carbo-nitrile.

The title compound, C22H16N4O2, crystallizes in the monoclinic space group P21/c with two independent mol-ecules, A and B, in the asymmetric unit. The isoxazole ring is inclined to the pyridine ring system, the indoline ring, and the phenyl ring by 8.00 (10), 70.93 (10), 35.89 (12), respectively, ° for mol-ecule A,and 4.24 (10), 84.62 (9),30.02 (11)° for mol-ecule B. In the crystal, mol-ecules are linked by C-H⋯O and C-H⋯N inter-actions, forming layers parallel to the (100) plane. In addition π-π inter-actions with centroid-to-centroid distances of 3.8057 (12) Å and a series of C-H⋯π inter-actions help to consolidate the packing in a three-dimensional architecture within the crystal. Additional electron density was localized in voids (398 Å3 solvent accessible volume) summing up to 92 electrons, which corresponds to approximately 3.5 mol-ecules of ethanol. The given chemical formula and other crystal data do not take into account the solvent.