Experimental cell research · 2024
Recent advances in the role of hydrogen sulfide in age-related diseases.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
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Zhang Chao-Jing, Wang Yan, Jin Yu-Qing, Zhu Yi-Wen, Zhu Shuai-Gang, Wang Qi-Meng, Jing Mi-Rong, Zhang Yan-Xia, Cai Chun-Bo, Feng Zhi-Fen, Ji Xin-Ying, Wu Dong-Dong
Аннотация
In recent years, the impact of age-related diseases on human health has become increasingly severe, and developing effective drugs to deal with these diseases has become an urgent task. Considering the essential regulatory role of hydrogen sulfide (H2S) in these diseases, it is regarded as a promising target for treatment. H2S is a novel gaseous transmitter involved in many critical physiological activities, including anti-oxidation, anti-inflammation, and angiogenesis. H2S also regulates cell activities such as cell proliferation, migration, invasion, apoptosis, and autophagy. These regulatory effects of H2S contribute to relieving and treating age-related diseases. In this review, we mainly focus on the pathogenesis and treatment prospects of H2S in regulating age-related diseases.