Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2009
[The expressions of PPAR-gamma, COX-2 in the lesions of patients with condyloma acuminatum and bowenoid papulosis].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Ni Jun, Zhang Yi-zhi, Xue Si-liang
Аннотация
OBJECTIVE: To investigate the expression of PPAR-gamma, COX-2 in the skin lesion of condyloma acuminatum and bowenoid papulosis.
METHODS: The expression levels of PPAR-gamma, COX-2 were measured by immunohistochemistry in 17 cases of condyloma acuminatum, 17 cases of bowenoid papulosis, as well as 17 cases of normal foreskin lesions.
RESULTS: The immunohistochemical study showed that PPAR-gamma and COX-2 weakly expressed in normal foreskin, but overexepressed in the skin lesions of both condyloma acuminatum and bowenoid papulosis (P<0.01). There was straight linear correlation between the expressions of PPAR-gamma and COX-2 not only in condyloma acuminatum (r=0.505, P=0.038) but also in bowenoid papulosis (r=0.562, P=0.019).
CONCLUSION: PPAR-gamma and COX-2 may have important roles in proliferative dermatosis associated with human papilloma virus.
METHODS: The expression levels of PPAR-gamma, COX-2 were measured by immunohistochemistry in 17 cases of condyloma acuminatum, 17 cases of bowenoid papulosis, as well as 17 cases of normal foreskin lesions.
RESULTS: The immunohistochemical study showed that PPAR-gamma and COX-2 weakly expressed in normal foreskin, but overexepressed in the skin lesions of both condyloma acuminatum and bowenoid papulosis (P<0.01). There was straight linear correlation between the expressions of PPAR-gamma and COX-2 not only in condyloma acuminatum (r=0.505, P=0.038) but also in bowenoid papulosis (r=0.562, P=0.019).
CONCLUSION: PPAR-gamma and COX-2 may have important roles in proliferative dermatosis associated with human papilloma virus.