Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology · 2008
[Expressions of interleukin 4 mRNA and interferonjgamma mRNA of condyloma acuminata].
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Ma Yong, Liu Tong
Аннотация
AIM: To study the expressions of interleukin 4 (IL-4) mRNA and interferon-gamma (IFN-gamma) mRNA of condyloma acuminata in order to obtain a clue as to the immunological mechanisms possibly relevant for warts regression or persistence.
METHODS: In situ RT-PCR was employed in surgically removed warts of 22 recurrent patients, 14 non-recurrent patients and 15 normal controls, respectively.
RESULTS: The expression of IFN-gamma mRNA in the non-recurrent warts was higher than in recurrent warts (P<0.01); but the expression of IL-4 mRNA in the recurrent warts was higher than in non-recurrent warts (P<0.01).
CONCLUSION: A higher IFN-gamma mRNA expression of condyloma acuminata lesions might contribute to warts regression.
METHODS: In situ RT-PCR was employed in surgically removed warts of 22 recurrent patients, 14 non-recurrent patients and 15 normal controls, respectively.
RESULTS: The expression of IFN-gamma mRNA in the non-recurrent warts was higher than in recurrent warts (P<0.01); but the expression of IL-4 mRNA in the recurrent warts was higher than in non-recurrent warts (P<0.01).
CONCLUSION: A higher IFN-gamma mRNA expression of condyloma acuminata lesions might contribute to warts regression.