Fertility and sterility · 1993
Ovarian superstimulation and intrauterine insemination for the treatment of unexplained infertility.
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Aboulghar M A, Mansour R T, Serour G I, Amin Y, Abbas A M, Salah I M
Аннотация
OBJECTIVE: To evaluate the efficacy of controlled ovarian hyperstimulation (COH) and IUI in the treatment of unexplained infertility.
DESIGN: The pregnancy rate (PR) in patients with unexplained infertility treated by COH and IUI (group A) was compared with a no-treatment control (group B).
SETTING: The Egyptian IVF-ET Center.
PARTICIPANTS: Four hundred ninety-two patients with the diagnosis of unexplained infertility.
INTERVENTION: Controlled ovarian hyperstimulation and IUI.
MAIN OUTCOME MEASURES: Cycle fecundity per treatment cycle and PR per patient.
RESULTS: In group A cycle fecundity was 20.1% per treatment cycle, and the PR was 34.7% per patient. In group B the PR was 8.9% per patient. Pregnancy rate per patient was significantly higher in group A when compared with the spontaneous PR in group B.
CONCLUSION: Controlled ovarian hyperstimulation and IUI significantly increased the PR in patients with unexplained infertility when compared with a no-treatment control group.
DESIGN: The pregnancy rate (PR) in patients with unexplained infertility treated by COH and IUI (group A) was compared with a no-treatment control (group B).
SETTING: The Egyptian IVF-ET Center.
PARTICIPANTS: Four hundred ninety-two patients with the diagnosis of unexplained infertility.
INTERVENTION: Controlled ovarian hyperstimulation and IUI.
MAIN OUTCOME MEASURES: Cycle fecundity per treatment cycle and PR per patient.
RESULTS: In group A cycle fecundity was 20.1% per treatment cycle, and the PR was 34.7% per patient. In group B the PR was 8.9% per patient. Pregnancy rate per patient was significantly higher in group A when compared with the spontaneous PR in group B.
CONCLUSION: Controlled ovarian hyperstimulation and IUI significantly increased the PR in patients with unexplained infertility when compared with a no-treatment control group.