Clinical neurophysiology practice · 2024
Can intravenous lorazepam prevent postictal generalized EEG suppression? A case report.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Ramilevich Zack, Zarroli Katherine
Аннотация
BACKGROUND: Postictal generalized electrographic suppression (PGES) may be considered an electrophysiological marker associated with an increased risk of sudden unexplained death in epilepsy (SUDEP).
CASE PRESENTATION: A case study is presented whereby a young man with focal to bilateral tonic-clonic seizures exhibited PGES after two spontaneously-aborted seizures; yet, after a third benzodiazepine-aborted seizure, PGES was absent.
CONCLUSION: This suggests that acutely administered benzodiazepines may offer direct anti-suppressive effects to prevent PGES, potentially reducing SUDEP risk.
CASE PRESENTATION: A case study is presented whereby a young man with focal to bilateral tonic-clonic seizures exhibited PGES after two spontaneously-aborted seizures; yet, after a third benzodiazepine-aborted seizure, PGES was absent.
CONCLUSION: This suggests that acutely administered benzodiazepines may offer direct anti-suppressive effects to prevent PGES, potentially reducing SUDEP risk.