[Study of the relation between dose of ionizing radiation and level of chromosome abnormalities in an adult patient following total body irradiation].

The dose-effect relationship for dicentric chromosome aberrations and centric rings was studied in a female patient exposed to whole-body gamma irradiation for myeloid leukaemia. Samples were taken before and at different times during the exposure. The dose-effect relationship is on the linear-quadratic type and practically identical with those found earlier when the blood from adults and children was irradiated in vitro and only slightly above that of children irradiated in vivo.