Physical-chemical analysis of dried Chamaeleo chamaeleon powder and evaluation of its aqueous extract antioxidation and antiangiogenesis activity.

Our research aims to characterize the physico-chemical properties of Chameleo chameleon powder, as well as to evaluate the potency of their compounds as antioxidants in aqueous extracts and their antiangiogenic activity. In this study, physicochemical characterization including pH, ash, some minerals, lipid, protein, carbohydrates and vitamins was investigated. The antioxidant capacity of the aqueous extract of C. chamaeleon was determined using DPPH free radical scavenging test and the superoxide radical scavenging test. The antiangiogenic activity was estimated using the chick chorioallantoic membrane assay. The obtained results demonstrate that the chameleon powder has a pH of 5.43 and a dry matter of 90.56%. The mineral richness is demonstrated by the ash result of 22.44% and the quantitative estimation revealed that it includes large levels of phosphorus. A high percentage of proteins, in contrast to carbohydrates and fats, with high values of the examined vitamins were also recorded. According to the results of the antioxidant test, the Chamaeleon extract was very effective in scavenging radicals. In terms of the anti-angiogenesis activity, the extract had very high effectiveness compared to DMSO. These findings lead us to conclude that Chamaeleon is a food supplement had significant antioxidant activity and high activity against angiogenesis.