[Quantitative determination of morphine in opium powder by addition and correlation method using capillary electrophoresis].

The morphine in opium powder has been quantitatively determined by addition and correlation method (ACM), in which capillary zone electrophoresis was applied, and the average recovery was 100.6%. The relative standard deviation (RSD) of migration time was not more than 2.4%, the RSD of relative migration time was not more than 1.1%, and the RSD of the relative area was not more than 0.51%. Meanwhile, the contrast test has been done by the calibration curve method with an internal standard correlation. The content of morphine in opium powder determined by ACM was the same as that by using the calibration curve method with an internal standard correlated. The study shows that ACM is simple, quick and accurate.