Journal of the International Society of Sports Nutrition · 2025
The effects of time-restricted eating combined with Tai Chi on glycolipid metabolism and endothelial function in postmenopausal women.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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Wang Xiao Yan, Chen Jiangang, Li Haojie
Аннотация
BACKGROUND: This study investigates the combined effects of time-restricted eating (TRE) and Tai Chi exercise (EX) on glycolipid metabolism and endothelial function in postmenopausal women, a population at heightened risk of metabolic and vascular disorders.
MATERIALS AND METHODS: A total of 142 postmenopausal women aged 50-60 years were randomly assigned to one of three groups: TRE combined with Tai Chi (TRE + EX, n = 47), TRE alone (n = 47), or a control group with conventional lifestyle (CON, n = 48). The TRE protocol required participants to consume all meals within an 8-hour window for 8 weeks, while the EX protocol involved three weekly 60-minute sessions of Yang-style 24-form Tai Chi. Outcomes included glycolipid markers, such as fasting plasma glucose, total cholesterol (Tot-Chol), and low-density lipoprotein cholesterol (LDL-C), as well as endothelial function assessed by flow-mediated dilation (FMD), nitric oxide (NO), and endothelin-1 (ET-1).
RESULTS: Significant group-by-time interactions were observed for Tot-Chol (p = 0.001) and LDL-C (p = 0.003), with the TRE + EX group showing the largest reductions compared to the TRE group (p = 0.030; p = 0.003) and the CON group (p = 0.000; p = 0.050). For FMD, a significant interaction was also observed (p = 0.003). Both the TRE + EX group and the TRE group showed significant improvements in FMD compared to baseline (p = 0.005; p = 0.044). However, only the TRE + EX group demonstrated significantly higher FMD than the CON group (p = 0.003).
CONCLUSION: The combination of TRE and Tai Chi was more effective in improving lipid profiles and endothelial function than TRE alone. These findings highlight the potential of integrating dietary timing with structured exercise as a strategy for enhancing metabolic and vascular health in postmenopausal women.
MATERIALS AND METHODS: A total of 142 postmenopausal women aged 50-60 years were randomly assigned to one of three groups: TRE combined with Tai Chi (TRE + EX, n = 47), TRE alone (n = 47), or a control group with conventional lifestyle (CON, n = 48). The TRE protocol required participants to consume all meals within an 8-hour window for 8 weeks, while the EX protocol involved three weekly 60-minute sessions of Yang-style 24-form Tai Chi. Outcomes included glycolipid markers, such as fasting plasma glucose, total cholesterol (Tot-Chol), and low-density lipoprotein cholesterol (LDL-C), as well as endothelial function assessed by flow-mediated dilation (FMD), nitric oxide (NO), and endothelin-1 (ET-1).
RESULTS: Significant group-by-time interactions were observed for Tot-Chol (p = 0.001) and LDL-C (p = 0.003), with the TRE + EX group showing the largest reductions compared to the TRE group (p = 0.030; p = 0.003) and the CON group (p = 0.000; p = 0.050). For FMD, a significant interaction was also observed (p = 0.003). Both the TRE + EX group and the TRE group showed significant improvements in FMD compared to baseline (p = 0.005; p = 0.044). However, only the TRE + EX group demonstrated significantly higher FMD than the CON group (p = 0.003).
CONCLUSION: The combination of TRE and Tai Chi was more effective in improving lipid profiles and endothelial function than TRE alone. These findings highlight the potential of integrating dietary timing with structured exercise as a strategy for enhancing metabolic and vascular health in postmenopausal women.