Nihon Jibiinkoka Gakkai kaiho · 2011
[A case report on cervical neuroblastoma with ataxia].
Клинический случайАннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Kanemura Nobuaki, Nakano Tomoaki, Hirano Ayako, Amatsu Hisao, Koshimo Naomi, Uemura Go, Aiba Tsunemasa
Аннотация
We present a case of pediatric primary cervical neuroblastoma (NB), which is extremely rare. A 3-year-old girl with ataxia but no nasal obstruction, dysphagia, or stridor was diagnosed with cervical NB. Diagnostic results including clinical chemistry, full blood count, and serology, were normal. Ataxia worsened within a few days after onset and was not cured by steroids or intravenous immunoglobulin, delaying a definite diagnosis until a tumor was detected. Opsoclonus-myoclonus syndrome is typified by opsoclonus with myoclonus and ataxia, primarily associated with neuroblastoma. Brain stem cell and cerebellum dysfunction is thought to be due to an autoimmune mechanism. Following chemotherapy and selective neck dissection, the girl has had no recurrence or adverse sequelae. Ataxia disappeared during chemotherapy. We suggest that neuroblastoma should be considered in any child with unexpected by prolonged ataxia.