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Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024

Cardioneuroablation for the management of patients with recurrent vasovagal syncope and symptomatic bradyarrhythmias: the CNA-FWRD Registry.

СтатьяМногоцентровое исследованиеНаблюдательное исследованиеНазвание и аннотация: Перевод в очереди
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Aksu Tolga, Tung Roderick, De Potter Tom, Markman Timothy M, Santangeli Pasquale, du Fay de Lavallaz Jeanne, Winterfield Jeffrey R, Baykaner Tina, Alyesh Daniel, Joza Jacqueline E, Gopinathannair Rakesh, Badertscher Patrick, Do Duc H, Hussein Ayman, Osorio Jose, Dewland Thomas, Perino Alexander, Rodgers Albert J, DeSimone Christopher, Alfie Alberto, Atwater Brett D, Singh David, Kumar Kapil, Salcedo Jonathan, Bradfield Jason S, Upadhyay Gaurav, Sood Nitesh, Sharma Parikshit S, Gautam Sandeep, Kumar Vineet, Forno Alexander Romeno Janner Dal, Woods Christopher E, Rav-Acha Moshe, Valeriano Chiara, Kapur Sunil, Enriquez Andres, Sundaram Sri, Glikson Michael, Gerstenfeld Edward, Piccini Jonathan, Tzou Wendy S, Sauer William, d'Avila Andre, Shivkumar Kalyanam, Huang Henry D

Аннотация

BACKGROUND: Cardioneuroablation has been emerging as a potential treatment alternative in appropriately selected patients with cardioinhibitory vasovagal syncope (VVS) and functional AV block (AVB). However the majority of available evidence has been derived from retrospective cohort studies performed by experienced operators.

METHODS: The Cardioneuroablation for the Management of Patients with Recurrent Vasovagal Syncope and Symptomatic Bradyarrhythmias (CNA-FWRD) Registry is a multicenter prospective registry with cross-over design evaluating acute and long-term outcomes of VVS and AVB patients treated by conservative therapy and CNA.

RESULTS: The study is a prospective observational registry with cross-over design for analysis of outcomes between a control group (i.e., behavioral and medical therapy only) and intervention group (Cardioneuroablation). Primary and secondary outcomes will only be assessed after enrollment in the registry. The follow-up period will be 3 years after enrollment.

CONCLUSIONS: There remains a lack of prospective multicentered data for long-term outcomes comparing conservative therapy to radiofrequency CNA procedures particularly for key outcomes including recurrence of syncope, AV block, durable impact of disruption of the autonomic nervous system, and long-term complications after CNA. The CNA-FWRD registry has the potential to help fill this information gap.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты