The Impact on Acne Treatment Regimens if Benzoyl Peroxide-Containing Products are Removed From the Market.

Benzyl peroxide (BPO) has been an important component of many acne treatment regimens. However, an independent testing laboratory, Valisure, filed a Citizen’s Petition with the US Food and Drug Administration (FDA) requesting the removal of BPO products from the market. Their testing demonstrated that when exposed to elevated temperatures which could occur during shipping, marketed BPO products can form over 800 times the FDA concentration limits of benzene, a class 1 carcinogen. In this review, we aim to describe what a post-BPO removal acne treatment regimen might look like based on currently approved products and products in late-stage development. Citation: Dhawan S, Nardo CJ. The impact on acne treatment regimens if benzoyl peroxide-containing products are removed from the market. J Drugs Dermatol. 2025;24(6):586-589. doi:10.36849/JDD.8840R1.